Physical Stability Test Spray 10% Combination of Virgin Coconut Oil (VCO) and Ginger (Zingiber Officinale Rocs.) As a candidate of a substance for the cure of gingivitis
##semicolon##
https://doi.org/10.59188/eduvest.v6i3.52657##semicolon##
Virgin Coconut Oil (VCO)##common.commaListSeparator## ginger (Zingiber officinale Rocs.)##common.commaListSeparator## gingivitis##common.commaListSeparator## spray physical stability##common.commaListSeparator## cycling testAbstrakt
Virgin Coconut Oil (VCO) and ginger (Zingiber officinale Rosc.) have antibacterial and anti-inflammatory activities, making them potential natural alternative therapies for the treatment of gingivitis. Although their biological effectiveness has been proven, the physical stability of this combination spray preparation has not yet been evaluated. The spray formulation was chosen because it is practical, provides even distribution, and minimises contamination. To determine the effect of physical stability testing of a 10% VCO-ginger spray combination as a candidate material for the treatment of gingivitis. Laboratory experimental research was conducted by creating five formulations (F1-F5). Stable formulations were subjected to a cycling test and physical stability evaluation, including organoleptic testing, homogeneity, pH, viscosity, spreadability, and adhesion. Data analysis was performed descriptively. Formulation F5 showed the best physical characteristics with a milky white colour, a distinctive coconut-ginger smell, a homogeneous liquid texture, a pH of 6.019-6.823, a spreadability of 5.0-6.1 cm, an adhesion of 19.27-29.72 seconds, and a viscosity of 346.7-692.8 cP. Formulation F5 has physical performance potential as a candidate for gingivitis therapy, but its emulsion stability is limited under extreme temperature conditions. Optimisation of surfactant concentration is required to prevent viscosity reduction and phase separation during long-term storage.
##submission.citations##
Abidin, J., Rianto, A. D., Kuswandi, A. A., Hidayat, Y., & Novalinda, N. A. (2022). Assistance for increasing farmers’ capacity in processing coconut fruit into virgin coconut oil (VCO) in Emplak Village Kalipucang District Pangandaran Regency. Mattawang: Jurnal Pengabdian Masyarakat, 3, 7–15. https://doi.org/10.35877/454RI.mattawang778
Adnyani, N., Aisyah, R., & Puspaningrat, L. (2023). Uji efektivitas formulasi sediaan spray ekstrak bunga kecombrang (Etlingera elatior (Jack) R.M.Sm.) sebagai repellent terhadap nyamuk Aedes aegypti. Jurnal Farmasi KRYONAUT, 2, 97–107. https://doi.org/10.59969/jfk.v2i2.69
Agustiani, F. R. T., Sjahid, L. R., & Nursal, F. K. (2022). Kajian literatur: Peranan berbagai jenis polimer sebagai gelling agent terhadap sifat fisik sediaan gel. Majalah Farmasetika, 7, 270. https://doi.org/10.24198/mfarmasetika.v7i4.39016
Almukainzi, M., Alotaibi, L., Abdulwahab, A., Albukhary, N., & El Mahdy, A. M. (2022). Quality and safety investigation of commonly used topical cosmetic preparations. Scientific Reports, 12, 18299. https://doi.org/10.1038/s41598-022-21771-7
Ambarwati, R., Andini, S., & Solihat, S. N. (2024). Formulasi dan evaluasi sediaan oral thin film ekstrak daun saga rambat (Abrus precatorius L.) dengan variasi konsentrasi PEG 400. Majalah Farmasetika, 9, 315–326. https://doi.org/10.24198/mfarmasetika.v9i4.55045
Angelia, A., Putri, G. R., Shabrina, A., & Ekawati, N. (2022). Formulasi sediaan spray gel ekstrak kulit jeruk manis (Citrus sinensis L.) sebagai anti-aging. Generics: Journal of Research in Pharmacy, 2, 44–53. https://doi.org/10.14710/genres.v2i1.13213
Anggraeni, I. A. B., Wartini, N. M., & Suhendra, L. (2022). Pengaruh kombinasi Tween 80 dan Span 80 sebagai emulsifier pada enkapsulasi ekstrak bunga kenikir menggunakan gum arab. Jurnal Rekayasa dan Manajemen Agroindustri, 10, 493. https://doi.org/10.24843/JRMA.2022.v10.i04.p10
Annisa, B. N., Fransiska, A. N., Malik, L. H., & Wulanbirru, P. (2020). Potensi jahe (Zingiber officinale Rosc.) untuk antiinflamasi dan antioksidan. HSG Journal, 5, 31–42. https://doi.org/10.35706/hsg.v5i2.4931
Ayuningtyas, D., Astuti, D. S., & Riyanta, A. B. (2021). Kemampuan jerami padi sebagai alternatif surfaktan alami dalam pembuatan sabun padat berbasis minyak goreng bekas. Parapemikir: Jurnal Ilmiah Farmasi, 10, 40. https://doi.org/10.30591/pjif.v10i1.2143
Azizah, A. V., Mulyani, S., & Suhendra, L. (2021). Mempelajari laju kerusakan krim kunyit–lidah buaya (Curcuma domestica Val.–Aloe vera) pada berbagai konsentrasi phenoxyethanol selama penyimpanan. Jurnal Rekayasa dan Manajemen Agroindustri, 9, 394. https://doi.org/10.24843/JRMA.2021.v09.i03.p12
Banne, Y., Maramis, R., Awitari, I., Dumanauw, J., Rindengan, E., Rumagit, B., & Sapiun, Z. (2022). Pembuatan sediaan spray repelen dari minyak atsiri bunga kamboja putih (Plumeria alba). Prosiding Seminar Nasional Kefarmasian Program Studi Farmasi FMIPA Universitas Sam Ratulangi, 1, 12–16.
Bouta, I. M., Abdul, A., & Kandowangko, N. Y. (2020). Nilai bilangan peroksida dan asam lemak bebas pada virgin coconut oil hasil fermentasi yang disuplementasi dengan kunyit (Curcuma longa L.). Jambura Edu Biosfer Journal, 2, 51–56. https://doi.org/10.34312/jebj.v2i2.4461
Carvajal, P., Gómez, M., Gomes, S., Costa, R., Toledo, A., Solanes, F., Romanelli, H., Oppermann, R., Rösing, C., & Gamonal, J. (2016). Prevalence, severity, and risk indicators of gingival inflammation in a multi-center study on South American adults: A cross-sectional study. Journal of Applied Oral Science, 24, 524–534. https://doi.org/10.1590/1678-775720160178
Cendana, Y., Adrianta, K. A., & Suena, N. M. D. S. (2021). Formulasi spray gel minyak atsiri kayu cendana (Santalum album L.). Jurnal Ilmiah Medicamento, 7, 84–89. https://doi.org/10.36733/medicamento.v7i2.2272
Chaerunisaa, A. Y., Husni, P., & Murthadiah, F. A. (2020). Modifikasi viskositas kappa karagenan sebagai gelling agent menggunakan metode polymer blend. Jurnal Indonesian Society of Integrated Chemistry, 12, 73–83. https://doi.org/10.22437/jisic.v12i2.12040
Darman, H. S., Asben, A., & Dewi, K. H. (2022). Pembuatan produk spray-dent dengan menggunakan ekstrak daun sirih hijau dan perasan jeruk nipis tanpa deterjen sebagai pembersih gigi pada anak usia dini. Jurnal Litbang Industri, 12, 49–60. https://doi.org/10.24960/jli.v12i1.7732.49-60
Dewi, R., Anwar, E., & Setyani, Y. K. (2015). Uji stabilitas fisik formula krim yang mengandung ekstrak kacang kedelai (Glycine max). Pharmaceutical Sciences and Research, 1(3). https://doi.org/10.7454/psr.v1i3.3484
Jacob, Anoop. (2016). Comparative Evaluation of Oil Pulling Using Virgin Coconut Oil, Refined Coconut Oil as Against Chlorhexidine Mouthwash on Streptococcus Mutans Count in Saliva”-An Invivo Study. Rajiv Gandhi University of Health Sciences (India).
Salian, Varsha, & Shetty, Pushparaja. (2018). Coconut Oil and Virgin Coconut Oil: An Insight into its Oral and Overall Health Benefits. Journal of Clinical & Diagnostic Research, 12(1).
Wallace, Taylor C. (2019). Health effects of coconut oil—A narrative review of current evidence. Journal of the American College of Nutrition, 38(2), 97–107.
##submission.downloads##
Publikované
##submission.howToCite##
Číslo
Sekcia
##submission.license##
##submission.copyrightStatement##
##submission.license.cc.by-sa4.footer##





