Perioperative Management in a Cesarean Section Patient with Rheumatic Heart Disease and Pulmonary Hypertension

Authors

  • Leonardo A. J. Lawalata Universitas Sam Ratulangi, Indonesia
  • Mordekhai L. Laihad Universitas Sam Ratulangi, Indonesia
  • Iddo Posangi Universitas Sam Ratulangi, Indonesia
  • Eka Y. Lantang Universitas Sam Ratulangi, Indonesia
  • Barry I. Kambey Universitas Sam Ratulangi, Indonesia

DOI:

https://doi.org/10.59188/eduvest.v6i3.52406

Keywords:

Anesthesia, Pulmonary, Hypertension, Heart, Pregnancy, Cesarean Section

Abstract

Background: Pregnancy complicated by rheumatic heart disease (RHD) and pulmonary hypertension (PH) is a high-risk condition with maternal mortality reaching 20–50%. The physiological burden of pregnancy can precipitate cardiovascular decompensation, making perioperative management of cesarean section extremely challenging. Objective: This case report aims to describe the perioperative challenges and the multidisciplinary anesthetic strategy implemented in a high-risk parturient with RHD and PH, emphasizing the rationale for choosing general anesthesia over regional techniques. Methods: A 25-year-old woman (G3P2A0) at 32–33 weeks gestation presented in labor with signs of fetal distress. She had a history of RHD with moderate-to-severe mitral stenosis, moderate tricuspid regurgitation, PH, and atrial fibrillation with rapid ventricular response. Due to significant coagulopathy (INR 2.3), regional anesthesia was contraindicated. The patient underwent general anesthesia with gradual induction, invasive hemodynamic monitoring (arterial and central venous lines), and lung-protective ventilation for an emergency cesarean section. Findings: The procedure was completed successfully with the delivery of a live infant with good Apgar scores. Intraoperatively, the patient remained hemodynamically stable with support from inotropes and vasopressors. Postoperatively, she was managed in the intensive care unit (ICU) for four days before being transferred to the general ward and discharged without major complications. Implications: This case underscores that in specific high-risk scenarios where regional anesthesia is contraindicated, a carefully conducted general anesthesia with invasive monitoring can be a safe and effective alternative.

References

Adare, O. E., Seife, M. A., & Abate, L. G. (2023). Perioperative anesthesia management for pregnant mother with multivalvular heart disease and moderate pulmonary hypertension who underwent caesarean section in a resource-limiting area: A case report. International Medical Case Reports Journal, 16, 311–317. https://doi.org/10.2147/IMCRJ.S403548

Ahmadzadeh, S., Duplechin, D. P., Bailey, P. D., Duplechan, D. T., Enache, A. J., Moore, P., & Shekoohi, S. (2025). Anesthetic management for delivery in parturients with heart disease: A narrative review. Biomedicines, 13(7), 1736. https://doi.org/10.3390/biomedicines13071736

Fraccaro, C., Tence, N., Masiero, G., & Karam, N. (2020). Management of valvular disease during pregnancy: Evolving role of percutaneous treatment. Interventional Cardiology, 15, e10. https://doi.org/10.15420/icr.2020.06

Futier, E., Lefrant, J.-Y., Guinot, P.-G., Godet, T., Lorne, E., Cuvillon, P., Bertran, S., Leone, M., Pastene, B., & Piriou, V. (2017). Effect of individualized vs standard blood pressure management strategies on postoperative organ dysfunction among high-risk patients undergoing major surgery: A randomized clinical trial. JAMA, 318(14), 1346–1357.

Hutt, E., & Desai, M. Y. (2020). Management of valvular heart disease in the pregnant patient. Expert Review of Cardiovascular Therapy, 18(8), 495–501. https://doi.org/10.1080/14779072.2020.1791353

Kachhwaha, A., Karagyozyan, D. S., Aluzri, N., & Vandse, R. (2025). Perioperative management of a pregnant patient with severe mitral stenosis and pulmonary hypertension for repeat cesarean section: The role of standby extracorporeal membrane oxygenation. Cureus, 17(8), e89986. https://doi.org/10.7759/cureus.89986

Maisat, W., & Yuki, K. (2024). The Fontan circulation in pregnancy: Hemodynamic challenges and anesthetic considerations. Journal of Cardiothoracic and Vascular Anesthesia, 38(11), 2770–2782.

Melaku, L. (2022). Physiological changes in pregnancy and anesthetic implication during labor, delivery, and postpartum. The Open Anesthesia Journal, 16(1).

Meng, M.-L., Arendt, K. W., Banayan, J. M., Bradley, E. A., Vaught, A. J., Hameed, A. B., Harris, J., Bryner, B., Mehta, L. S., & American Heart Association Council on Cardiovascular Surgery and Anesthesia, Council on Cardiopulmonary, Perioperative and Resuscitation, and Council on Peripheral Vascular Disease. (2023). Anesthetic care of the pregnant patient with cardiovascular disease: A scientific statement from the American Heart Association. Circulation, 147(11), e657–e673.

Minhas, A. S., Rahman, F., Gavin, N., Cedars, A., Vaught, A. J., Zakaria, S., et al. (2021). Cardiovascular and obstetric delivery complications in pregnant women with valvular heart disease. The American Journal of Cardiology, 158, 90–97. https://doi.org/10.1016/j.amjcard.2021.07.038

Passos, L. S. A., Nunes, M. C. P., & Aikawa, E. (2021). Rheumatic heart valve disease pathophysiology and underlying mechanisms. Frontiers in Cardiovascular Medicine, 7, 612716.

Pichette, M., Liszkowski, M., & Ducharme, A. (2017). Preoperative optimization of the heart failure patient undergoing cardiac surgery. Canadian Journal of Cardiology, 33(1), 72–79.

Remenyi, B., ElGuindy, A., Smith, S. C., Yacoub, M., & Holmes, D. R. (2016). Valvular aspects of rheumatic heart disease. The Lancet, 387(10025), 1335–1346.

Simpson, M. T., Kachel, M., Neely, R. C., Erwin, W. C., Yasin, A., Patel, A., Rao, D. P., Pandey, K., & George, I. (2023). Rheumatic heart disease in the developing world. Structural Heart, 7(6), 100219. https://doi.org/10.1016/j.shj.2023.100219

Singh, M., Abraham, A., Soni, S. C., & Singh, S. (2025). Perioperative challenges and management strategies for non-cardiac surgery in patients with rheumatic heart diseases: A narrative review. Journal of Anaesthesiology Clinical Pharmacology, 41(3), 384–395. https://doi.org/10.4103/joacp.joacp_167_24

Söner, H. T., Bulut, E., Uzundere, O., Söner, S., Baysal Yıldırım, Z., & Kuyumcu, M. (2023). Management of anesthesia in pregnant women with pulmonary hypertension. European Review for Medical and Pharmacological Sciences, 27(23), 11315–11322.

Unger, P., Pibarot, P., Tribouilloy, C., Lancellotti, P., Maisano, F., Iung, B., Piérard, L., & ESC Council on Valvular Heart Disease. (2018). Multiple and mixed valvular heart diseases: Pathophysiology, imaging, and management. Circulation: Cardiovascular Imaging, 11(8), e007862.

Youssef, G. (2021). Valvular heart diseases in women. Egyptian Heart Journal, 73, 58. https://doi.org/10.1186/s43044-021-00184-3

Zaza, K. J., Abdalla, E. O. I., & Alhammad, M. F. (2026). Optimizing postoperative fluid and electrolyte care in cardiac surgery patients. In Perioperative Care of Cardiac Surgery Patients (pp. 159–182).

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Published

2026-03-06

How to Cite

J. Lawalata, L. A., Laihad, M. L. ., Posangi, I. ., Lantang, E. Y. ., & Kambey, B. I. . (2026). Perioperative Management in a Cesarean Section Patient with Rheumatic Heart Disease and Pulmonary Hypertension. Eduvest - Journal of Universal Studies, 6(3), 3224–3233. https://doi.org/10.59188/eduvest.v6i3.52406