Nursing Intervention for Incidence Phlebitis Prevention in Adult Patient: A Systematic Review

Authors

  • Albertina Dete Tabik Universitas Airlangga
  • Abu Bakar Universitas Airlangga
  • Ika Nur Pratiwi Universitas Airlangga

DOI:

https://doi.org/10.59188/eduvest.v6i1.52374

Keywords:

Nurse Intervention, Prevention, Incidence Phlebitis

Abstract

Phlebitis refers to the inflammation or irritation of the vein wall, often caused by mechanical, chemical, or bacterial factors. Mechanical phlebitis is related to the action of the peripheral intravenous catheter (PIVC), chemical phlebitis arises from infusates or medications, and bacterial phlebitis is due to contamination at the insertion site or in the intravenous solution or tubing. Catheter-associated bloodstream infections (CABSI) can significantly increase healthcare costs, with treatment costs ranging from $3,000 to $56,000 per episode and prolonged hospital stays averaging 7 to 14 days (Marsh et al., 2024). This study, titled Nursing Intervention for Incidence Phlebitis Prevention in Adult Patient: A Systematic Review, aims to identify effective interventions that can be adopted by healthcare facilities, particularly in wards, to prevent phlebitis. This article analyzes data from six databases: Scopus, PubMed, ProQuest, ScienceDirect, Google Scholar, and Web of Science, focusing on articles published between 2019 and 2025. A total of 10 articles with randomized controlled trial (RCT) designs, scoring above 70% on the JBI assessment, were selected. The results indicate that moist heat therapy significantly improved vein visibility and palpability, reduced pain during cannulation, and increased first-attempt success to 93.3%. Clinically indicated catheter removal was found to be as effective as routine 96-hour replacement for preventing phlebitis.

References

Aksoy, F., & Bayram, S. B. (2023). The effect of warm moist compresses in peripheral intravenous catheter-related phlebitis. European Journal of Oncology Nursing, 67. https://doi.org/10.1016/j.ejon.2023.102438

Anitarini, F., Dwiantoro, L., & Santoso, A. (2020). Sistematik Review: Bagaimana Cara Meningkatkan Caring Perawat (Sistematic Review: How to Improve Nursing Caring). 34. https://doi.org/10.20473/fmnj.v2i2.19651

Anne Mercado, Z., & Paul Musco, S. (2022). Effect of Local Heat Application on First Peripheral Access Attempt Success Among Identified High-Risk Difficult Intravenous Access (DIVA) by Ambulatory Surgical Nurses A Clinical Scholarly Project by.

Cabrero, E. L., Robledo, R. T., Cuñado, A. C., Sardelli, D. G., Huerta, C. M., Perez, L. L., Estevez, P. E., Esquinas, C., & Tortosa, A. (2024). The Midline Catheter Within the Context of Home Intravenous Antibiotic Treatment. Journal of Infusion Nursing, 47(6), 369–376. https://doi.org/10.1097/NAN.0000000000000559

Chen, X. (2025). PDCA cycle and safety culture in nursing safety management of Day Ward chemotherapy. World Journal of Surgical Oncology , 23(1). https://doi.org/10.1186/s12957-025-03738-w

Cho, S., & Kim, E. M. (2025). Quality Improvement Interventions for Peripheral Intravenous Catheter Nursing Practices: A Systematic Review. Journal of Nursing Care Quality. https://doi.org/10.1097/NCQ.0000000000000853

Ferraz-Torres, M., Sancho-Sena, E., Corcuera-Martinez, M. I., Martinez-Garcia, O., & Suarez-Mier, M. B. (2024). Complications Related to the Securement Device in Peripheral Intravenous Catheters: A Randomized Study. Journal of Infusion Nursing : The Official Publication of the Infusion Nurses Society, 47(6), 391–396. https://doi.org/10.1097/NAN.0000000000000561

Garcia-Expósito, J., Sánchez-Meca, J., Almenta-Saavedra, J. A., Llubes-Arrià, L., Torné-Ruiz, A., & Roca, J. (2023). Peripheral venous catheter-related phlebitis: A meta-analysis of topical treatment. In Nursing Open (Vol. 10, Issue 3, pp. 1270–1280). John Wiley and Sons Inc. https://doi.org/10.1002/nop2.1449

Kaphan, K., Auypornsakul, S., Somno, J., Wongwattananan, W., Jamsittikul, K., Baicha, W., Somsri, S., & Sawatrak, T. (2024a). The Prevalence and Associated Factors of Peripheral Intravenous Complications in a Thai Hospital. Journal of Infusion Nursing, 47(2), 120–131. https://doi.org/10.1097/NAN.0000000000000538

Kaphan, K., Auypornsakul, S., Somno, J., Wongwattananan, W., Jamsittikul, K., Baicha, W., Somsri, S., & Sawatrak, T. (2024b). The Prevalence and Associated Factors of Peripheral Intravenous Complications in a Thai Hospital. Journal of Infusion Nursing, 47(2), 120–131. https://doi.org/10.1097/NAN.0000000000000538

Lopes, G. F., Oliveira, V. de C., Monteiro, R. M., Amadio Domingues, P. C., Bim, F. L., Bim, L. L., Ferreira da Silva, G. B., Pereira dos Santos, A., do Nascimento, C., de Andrade, D., & Watanabe, E. (2024). Assessment of peripheral venous catheters microbiota and its association with phlebitis. Infection, Disease and Health. https://doi.org/10.1016/j.idh.2024.07.005

Marsh, N., Larsen, E. N., Ullman, A. J., Mihala, G., Cooke, M., Chopra, V., Ray-Barruel, G., & Rickard, C. M. (2024). Peripheral intravenous catheter infection and failure: A systematic review and meta-analysis. In International Journal of Nursing Studies (Vol. 151). Elsevier Ltd. https://doi.org/10.1016/j.ijnurstu.2023.104673

Oliveira, F., Gomes, I., & Oliveira, A. R. C. (2024). THE EFFECTIVENESS OF A SYSTEMATIZED NURSING CARE INTERVENTION IN THE PREVENTION AND IDENTIFICATION OF PHLEBITIS. Millenium: Journal of Education, Technologies, and Health, 2024(14e). https://doi.org/10.29352/mill0214e.33949

Park, Y., & Choi, S. (2025). Factors Affecting the Direct and Indirect Performance of Infection Control for Centrally Inserted Central Catheters Among ICU Nurses. Healthcare (Switzerland), 13(9). https://doi.org/10.3390/healthcare13090988

Pereira, V. H., de Almeida Cruz, M. C. M., Galon, T., da Cunha Januário, G., Contim, D., Dos Santos, M. A., Monteiro, D. A. T., & Toffano, S. E. M. (2024). Prevention And Control Of Infection Related To Peripheral Arterial Catheter Management. In Texto e Contexto Enfermagem (Vol. 33). Universidade Federal de Santa Catarina. https://doi.org/10.1590/1980-265X-TCE-2023-0208en

Salleras-Duran, L., Fuentes-Pumarola, C., Fontova-Almató, A., Roqueta-Vall-Llosera, M., Cámara-Liebana, D., & Ballester-Ferrando, D. (2024). Pain and Satisfaction Perceptions of Ultrasound-Guided Versus Conventional Peripheral Intravenous Catheterization: A Randomized Controlled Trial. Pain Management Nursing, 25(1), e37–e44. https://doi.org/10.1016/j.pmn.2023.07.010

Sulistyorini, S., Triana, W. Y., Chayatin, N., Priyantini, D., Ayatulloh, D., Nursalam, N., & Krisnana, I. (2022). Efektivitas Assessment Peripheral Vascular Access Device (PVAD) terhadap Pencegahan Plebhitis. Journal of Telenursing (JOTING), 4(2), 921–931. https://doi.org/10.31539/joting.v4i2.4031

Susriyanti, S., Krisna, N. L., Lusiana, L., & Nardo, R. (2023). Creating customer loyalty through commitment to quality of service model of brady cronin. International Journal of Applied Management and Business, 1(1), 32–47.

Tosun, B., Güngör, S., Ağkale, E., & Andı, S. (2024). Evaluation of the effect of proximal massage and palm fisting in reducing the risk of peripheral venous catheter-related phlebitis: randomized control study. European Journal of Cardiovascular Nursing, 23(6), 644–651. https://doi.org/10.1093/eurjcn/zvae024

Yasuda, H., Rickard, C. M., Marsh, N., Yamamoto, R., Kotani, Y., Kishihara, Y., Kondo, N., Sekine, K., Shime, N., Morikane, K., & Abe, T. (2022). Risk factors for peripheral intravascular catheter-related phlebitis in critically ill patients: analysis of 3429 catheters from 23 Japanese intensive care units. Annals of Intensive Care, 12(1). https://doi.org/10.1186/s13613-022-01009-5

Downloads

Published

2026-01-13

How to Cite

Tabik, A. D., Bakar, A. ., & Pratiwi, I. N. . (2026). Nursing Intervention for Incidence Phlebitis Prevention in Adult Patient: A Systematic Review. Eduvest - Journal of Universal Studies, 6(1), 734–744. https://doi.org/10.59188/eduvest.v6i1.52374