Vol 1, No 1, February -, 2021

p-ISSN 2775-3735- e-ISSN 2775-3727

Kirnia Tri Wulandari, Tikto

A PATIENT WITH EXPANDED DENGUE SYNDROM

Kirnia Tri Wulandari, Tikto

RSUD Dolopo

E-mail: kirnia.wulandari@gmail.com, [email protected]

Accepted:

Revised:

Approved:

Abstract

EDS is an atypical manifestation of dengue infection that

affects a variety of organ systems including

gastrointestinal, hepatic, neurological, cardiac,

pulmonary, and renal. It is one of the leading causes of

hospitalization and death in children. A number of

hypotheses have been proposed, but multifactorial

pathogenesis. Severe cases can be expressed with

petechiae, epistaxis, gastrointestinal hemorrhage, ascites,

pleural effuse, heart attack, hypotension, tachycardia,

changes in consciousness, fulminant hepatitis, and

myocarditis. EDS-shaped organ dysfunction may require

multidisciplinary management support for aggressive and

effective action. The baby girl, An.P, 10 months old, came

to the ER with a high fever since 4 days before KRS. High

fever accompanied by vomiting and diarrhea. From a

physical examination, the general condition of mentis

compost, pulse, and breathing within normal limits.

There are no epistaxis. The laboratory showed platelets

of 100,000 μ/L, hematocrit 35.5%, hemoglobin (Hb)

12.3g/dL. Patients are diagnosed with dengue fever. in

the same case that occurs in Mexico this is a case where

patients with fever and headache. Patients exhibit

neurological damage in which cranial Computerized

Axial Tomography (CAT) reveals severe cerebral edema.

Platelets 143,000 μ /L, Hb 10.6 g / dL, reported serologic

NS1 positive. Patients die five days after hospital

admission.Low incidence of EDS due to asymptomatic

and easily missed diagnosis. This case has multi-organ

failure. neurological manifestations such as seizures and

decreased consciousness, gastrointestinal manifestations

such as ascites and gastrointestinal bleeding, lung

manifestations such as dyspnea. Conditions worsen in a

fast time.

Keywords: Patient, Expanded and syndrome

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A Patient With Expanded Dengue Syndrom

http://eduvest.greenvest.co.id

INTRODUCTION

EDS is an atypical manifestation of dengue infection that affects a variety of

organ systems including gastrointestinal, hepatic, neurological, cardiac,

pulmonary, and renal. It is one of the leading causes of hospitalization and death

in children. A number of hypotheses have been proposed, but multifactorial

pathogenesis. Severe cases can be expressed with petechiae, epistaxis,

gastrointestinal bleeding, ascites, pleural effuse, heart attack, hypotension,

tachycardia, changes in consciousness, fulminant hepatitis, and myocarditis.

Organ dysfunction-shaped EDS may require multidisciplinary management

support for aggressive and effective action.

RESEARCH METHOD

The baby girl, An.P, 10 months old, came to the ER with a high fever

since 4 days before KRS. High fever accompanied by vomiting and diarrhea.

From a physical examination, the general condition of mentis compost, pulse, and

breathing within normal limits. There are no epistaxis. The laboratory showed

platelets of 100,000 μ/L, hematocrit 35.5%, hemoglobin (Hb) 12.3g/dL. The

patient was diagnosed with dengue fever. Patients are given infusion of Ringer

Lactat and antipyretics. After 2 days of hospitalization, the condition worsens

with the appearance of seizures and decreased consciousness. Oxygen therapy and

diazepam injection are given. An hour later, the patient had dyspnea.

Laboratprium results show patelet 29,000 μ/L. Somnolen patients, increased

respiration and interconstal retraction. Intravenous (IV) fluids are replaced with

gelafusin and dexamethasone injection therapy is given. 6 hours later, the patient

was melena and hb levels were low (6.6 g/dL). Patients sopor and desaturase.

Patients get a two-track infusion and a blood transfusion. The apnea patient an

hour later and died

Vol 1, No 1, February -, 2021

p-ISSN 2775-3735- e-ISSN 2775-3727

Kirnia Tri Wulandari, Tikto

RESULT AND DISCUSSION

In the same case that occurs in Mexico this is the case where the patient

with fever and headache. Patients exhibit neurological damage in which cranial

Computerized Axial Tomography (CAT) reveals severe cerebral edema. Platelets

143,000 μ /L, Hb 10.6 g / dL, reported serologic NS1 positive. The patient died

five days after hospital admission. Cases of dengue fever with neurological

manifestations have a higher risk of death, as reported in a study in Brazil, with a

mortality rate of 1.9%.

A Patient With Expanded Dengue Syndrom

http://eduvest.greenvest.co.id

CONCLUSION

Low incidence of EDS due to asymptomatic and diagnosis is easily

missed. This case has multi-organ failure. neurological manifestations such as

seizures and decreased consciousness, gastrointestinal manifestations such as

ascites and gastrointestinal bleeding, lung manifestations such as dyspnea.

Conditions worsen in a fast time.

REFERENCES

Gubbler DJ, Epidemic dengue/Dengue Hemorrhagic Fever as Public Helath.

Social and Economic Problem in 21st Century, Trends in Microbiology, Vol

10 (2), February, 2007: 100-103.

IDAI, 2014. Pedoman Diagnosis dan Tatalaksana Infeksi Dengue pada Anak;

UKK Infeksi dan Penyakit Tropis, IDAI

WHO Regional Office for South-East Asia, 2011, Comprehensive Guidlines for

Prevention and Control of Dengue and Dengue Haemorhagic Fever. New

Delhi; WHO, SEARO, Resived and Expanded Edition..